All Publications

Modular Synthesis of Cyclic Peptidomimetics Inspired by -Turns
Senthil Kumar Ramanathan, John Keeler, Huey-Lih Lee, D. Srinavasa Reddy, Gerald Lushington, and Jeffrey Aubé
Organic Letters, 2005, 7, 1059-1062
Facile C–N Cleavage in a Series of Bridged Lactams
Yao Lei, Aaron D. Wrobleski, Jennifer E. Golden, Douglas R. Powell, and Jeffrey Aubé
Journal of the American Chemical Society, 2005, 127, 4552-4553
Synthesis of a Small Library of Diketopiperazines as Potential Inhibitors of Calpain
Yibin Zeng, Qingshan Li, Robert P. Hanzlik, and Jeffrey Aubé
Bioorganic and Medicinal Chemistry Letters, 2005, 15, 3034–3038
Regioselective Single and Double Conjugate Additions to Substituted Cyclohexa-2,5-Dienone Monoacetals
Scott Grecian, Aaron D. Wrobleski, and Jeffrey Aubé
Organic Letters, 2005, 7, 3167–3170
Amides and Derivatives; Polyamides and Peptides: Lactams. 21.1.5. Product Subclass 1: Synthesis by Rearrangement
Weston Judd, Christopher E. Katz, and Jeffrey Aubé
George Thieme Verlag KG: Stuttgart, 2005, 133–178

An Expeditious Total Synthesis of (±)-Stenine
Yibin Zeng and Jeffrey Aubé
Journal of the American Chemical Society, 2005, 127, 15712–15713
Revisiting a Classic Approach to the Aspidosperma Alkaloids: An Intramolecular Schmidt Reaction-Mediated Synthesis of (+)-Aspidospermidine
Rajesh Iyengar, Klaas Schildknegt, Martha Morton, and Jeffrey Aubé
Journal of Organic Chemistry, 2005, 70, 10645-10662
Cyclization of a Carbon-Centered Radical Derived from Oxaziridine Cleavage
Yoshinosuke Usuki, Xin Peng, Belgin Gülgeze, and Jeffrey Aubé
Arkivoc, 2006, part iv, 189–199
Remote Control of Diastereoselectivity in Intramolecular Reactions of Chiral Allylsilanes
Weston R. Judd, Sooho Ban, and Jeffrey Aubé
Journal of the American Chemical Society, 2006, 128, 13736–13741
Solution-Phase Parallel Synthesis of a Library of 2-Pyrazolines
Shankar Manyem, Mukund P. Sibi, Gerald H. Lushington, Benjamin Neuenswander, Frank Schoenen, and Jeffrey Aubé
Journal of Combinatorial Chemistry, 2007, 9, 20–28
Cation– Control of Regiochemistry of Intramolecular Schmidt Reactions en Route to Bridged Bicyclic Lactams
Lei Yao and Jeffrey Aubé
Journal of the American Chemical Society, 2007, 129, 2766–2767
One-Step Synthesis of Oxazoline and Dihydrooxazine Libraries
Priyanka Chaudhry, Frank Schoenen, Benjamin Neuenswander, Gerald H. Lushington, and Jeffrey Aubé
Journal of Combinatorial Chemistry, 2007, 9, 473–476
Intramolecular and Intermolecular Schmidt Reactions of Alkyl Azides with Aldehydes
Huey-Lih Lee and Jeffrey Aubé
Tetrahedron, 2007, 63, 9007–9015
Synthesis of an N-Substituted Lactam Using an Intramolecular Schmidt Reaction
Scott Grecian and Jeffrey Aubé
Organic Syntheses, 2007, 84, 347–358
Double Conjugate Addition of a Nitropropionate Ester to a Quinone Monoketal: Synthesis of an Advanced Intermediate to (±)-Gelsemine
Scott Grecian and Jeffrey Aubé
Organic Letters, 2007, 9, 3153–3156
Synthesis of Isoquinol-1-one-8-carboxylic Acid Libraries Using a Tandem Diels–Alder/Acylation Sequence
Kevin J. Frankowski, Erin E. Hirt, Yibin Zeng, Ben Neuenswander, Drew Fowler, Frank Schoenen, and Jeffrey Aubé
Journal of Combinatorial Chemistry, 2007, 9, 1188–1192
Reactions of Cyclopropanone Acetals with Alkyl Azides: Carbonyl Addition versus Ring-Opening Pathways
Scott Grecian, Pankaj Desai, Craig Mossman, Jennifer L. Poutsma, and Jeffrey Aubé
Journal of Organic Chemistry, 2007, 72, 9439–9447
Nucleophilic Addition to Iminium Ethers in the Preparation of Functionalized N-Alkyl Heterocycles
Erik Fenster, Brenton T. Smith, Vijaya Gracias, Gregory L. Milligan, and Jeffrey Aubé
Journal of Organic Chemistry, 2008, 73, 201–205
Synthesis of Enantiomerically Enriched (R)-5-tert-Butylazepan-2-one Using a Hydroxyalkyl-azide Mediated Ring Expansion Reaction
Timothy P. Ribelin and Jeffrey Aubé
Nature: Protocols, 2008, 3, 137–143
Three-Component Synthesis of 1,4-Diazepin-5-ones and the Construction of γ Turn-like Peptidomimetic Libraries
Erik Fenster, Dinesh K. Rayabarapu, Mianji Zhang, Shubhasish Mukherjee, David Hill, Ben Neuenswander, Frank Schoenen, Paul R. Hanson, and Jeffrey Aubé
Journal of Combinatorial Chemistry, 2008, 10, 230–234
Efficient Synthesis of γ-Lactams by a Tandem Reductive Amination/Lactamization Sequence
Julica Nöth, Kevin J. Frankowski, Benjamin Neuenswander, Jeffrey Aubé, and Oliver Reiser
Journal of Combinatorial Chemistry, 2008, 10, 456–459
Syntheses of the Stemona Alkaloids (±)-Stenine, (±)-Neostenine, and (±)-13-Epineostenine Using a Stereodivergent Diels–Alder/Azido-Schmidt Reaction
Kevin J. Frankowski, Jennifer E. Golden, Yibin Zeng, Yao Lei, and Jeffrey Aubé
Journal of the American Chemical Society, 2008, 130, 6018–6024
Non-Bonded, Attractive Cation– Interactions in Azide-Mediated Asymmetric Ring Expansion Reactions
Christopher E. Katz, Timothy Ribelin, Donna Withrow, Yashar Basseri, Anna K. Manukyan, Amy Bermudez, Christian G. Nuera, Victor W. Day, Douglas R. Powell, Jennifer L. Poutsma, and Jeffrey Aubé
Journal of Organic Chemistry, 2008, 73, 3318 - 3327
Highly Stereoselective Ring Expansion Reactions Mediated by Attractive, Non-Bonded Cation–n Interactions
Timothy Ribelin, Christopher E. Katz, Donna G. English, Sherriel Smith, Anna Manukyan, Victor W. Day, Benjamin Neuenswander, Jennifer L. Poutsma, and Jeffrey Aubé
Angewandte Chemie, International Edition, 2008, 47, 6233–6235
Explorations of Stemona Alkaloid-Inspired Analogues: Skeletal Modification and Functional Group Diversification
Kevin J. Frankowski, Benjamin Neuenswander, and Jeffrey Aubé
Journal of Combinatorial Chemistry, 2008, 10, 721-725
The Total Synthesis of Amphibian Alkaloids Using the Intramolecular Schmidt Reaction
Kevin J. Frankowski, Aaron Wrobleski and Jeffrey Aubé,
Elsevier: Amsterdam, 2008, 408–459

Synthesis and Structural Study of Cyclic 5-Aminovaleric Acid-linked -Ala–-Ala Dipeptides
Anne Mengel, Oliver Reiser, and Jeffrey Aubé
Bioorganic & Medicinal Chemistry Letters, 2008, 18, 5975-5977
Stability of Medium-Bridged Twisted Amides in Aqueous Solutions
Michal Szostak, Lei Yao, and Jeffrey Aubé
Journal of Organic Chemistry, 2009, 74, 1869–1875
“Direct Synthesis of Medium-Bridged Twisted Amides via a Transannular Cyclization Strategy
Michal Szostak and Jeffrey Aubé
Organic Letters, 2009, 11, 3878–3881
Asymmetric Total Synthesis of Alkaloids 223A and 6-epi-223A
Partha Ghosh, Weston R. Judd, Timothy Ribelin, and Jeffrey Aubé
Organic Letters, 2009, 11, 4140–4142
Corey–Chaykovsky Epoxidation of Twisted Amides: Synthesis and Reactivity of Bridged Spiro-epoxyamines
Michal Szostak and Jeffrey Aubé
Journal of the American Chemical Society, 2009, 131, 13246–13247
Schmidt Rearrangement Reactions with Alkyl Azides
Scott Grecian and Jeffrey Aubé
John Wiley and Sons: Chichester, UK, 2009, pp 191-237

Cation−n Control of Regiochemistry of Intramolecular Schmidt Reactions en Route to Bridged Bicyclic Lactams
Michal Szostak, Lei Yao, and Jeffrey Aubé
Organic Letters, 2009, 11, pp 4386–4389
One-pot Synthesis of Lactams Using Domino Reactions: Combination of Schmidt Reaction with Sakurai and Aldol Reactions
Chan Woo Huh, Gagandeep K. Somal, Christopher E. Katz, Huaxing Pei, Yibin Zeng, Justin T. Douglas, and Jeffrey Aubé
Journal of Organic Chemistry, 2009, 74, 7618–7626
Synthesis and Rearrangement of a Bridged Thioamide
Michal Szostak and Jeffrey Aubé
Chemical Communications, 2009, 7122–7124

Publications