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Recent Publications
264
HuR-dependent Expression of Wisp1 Is Necessary for TGF-Induced Cardiac Myofibroblast Activity
Lisa C Green, Samuel Slone, Sarah R. Anthony, Adrienne Guarnieeri, Sharon Parkins, Shannon M. Shearer, Michelle L. Nieman, Sudeshna Roy, Jeffrey Aubé, Xiaoqing Wu, Liang Xu, Onur Kanisicak, and Michael Trantner
Journal of Molecular and Cellular Cardiology, 2023, 174, 38–46
263
HFIP in Organic Synthesis
Hashim F. Motiwala, Ahlam M. Armaly, Jackson G. Cacioppo, Thomas C. Coombs, Kimberly Koehn, Verrill M. Norwood IV, and Jeffrey Aubé
Chemical Reviews, 2022, 122, 12544–12747
261
Use of a MAIT-Activating Ligand, 5-OP-RU, as a Mucosal Adjuvant in a Murine Model of Vibrio cholerae O1 Vaccination
Owen Jensen, Shubhanshi Trivedi, Kelin Li, Jeffrey Aubé, J. Scott Hale, Edward T. Ryan, and Daniel T. Leung
Pathogens and Immunology, 2022, 7, 122–144
260
Small Molecule Disruptors of Mutant Huntingtin–Calmodulin Protein–Protein Interaction Attenuate Deleterious Effects of Mutant Huntingtin
Khushboo Kapadia, Ashley E. Trojniak, Kenneth B. Guzmán Rodríguez, Nicholas J. Klus, Coral Huntley, Peter McDonald, Anuradha Roy, Kevin J. Frankowski, Jeffrey Aubé, and Nancy A. Muma
ACS Chemical Neuroscience, 2022, 13, 2315–2337
259
Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis
Kevin J. Frankowski, Samarjit Patnai, Chen Wang, Noel Southall, Dipannita Dutta, Soumitta De, Dandan Li, Christopher Dextras, Yi-Han Lin, Marthe Bryant-Connah Danielle Davis, Feijun Wang, Leah M. Wachsmuth, Pranav Shah, Jordan Williams, Md Kabir, Edward Zhu, Bolormaa Baljinnyam, Amy Wang, Xin Xu, John Norton, Marc Ferrer, Steve Titus, Anton Simeonov, Wei Zheng, Lesley A. Mathews Griner, Ajit Jadhav, Jeffrey Aubé, Mark J. Henderson, Udo Rudloff, Frank J. Schoenen, Sui Huang, Juan J. Marugan
Journal of Medicinal Chemistry, 2022, 65, 8303–8331
258
Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance
Huiyong Ma, Tarsis Brust, Kevin J. Frankowski, Kimberly M. Lovell, Michael D. Cameron, Laura M. Bohn, and Jeffrey Aubé
ACS Chemical Neuroscience, 2022, 13, 1315–1332
257
SHAPE-enabled Fragment-Based Ligand Discovery for RNA
Meredith Zeller, Oleg Favorov, Kelin Li, Ashok Nuthanakanti, Dina Hussein, Aureliane Michaud, Daniel A Lafontaine, Steven Busan, Jeffrey Aubé, Alexander Serganov, and Kevin M. Weeks
Proceedings of the National Academy of Sciences, USA, 2022, 119, e2122660119
256
Use of AD Informer Set Compounds to Explore Validity of Novel Targets in Alzheimer’s Disease Pathology
Frances M. Potjewyd, Joel K. Annor-Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles Travis Moerk, Felix Nwogbo, Kenneth H. Pearce Jr., Timothy Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman
Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2022, 8, e12253
255
Identification of -Lactams Active Against Mycobacterium Tuberculosis by a Collaborative Consortium of Pharmaceutical Companies and Academic Institutions
Ben Gold, David Zhang, Landys Lopez Quezada, Julia Roberts, Yan Ling, Madeleine Wood, Wasima Shinwari, Laurent Goullieux, Christine Roubert, Laurent Fraisse, Eric Bacqué, Sophie Lagrange, Michal Vieth, Phil Hipskind, Lou Jungheim, Jeffrey Aubé, Sarah Scarry, Stacey McDonald, Kelin Li, Andrew Perkowski, Quyen Nguyen, Véronique Dartois, Matthew Zimmerman, David Olsen, Katherine Young, Shilah Bonnett, Douglas Joerss, Tanya Parish, Helena Boshoff, Kriti Arora, Clifton E. Barry III, Charlie Weatherall1, Laura Guijarro, Sara Anca, Joaquín Rullas, Beatriz Rodríguez-Salguero, Maria S. Martínez-Martínez, Esther Porras-De Francisco, Monica Cacho-Izquierdo, David Barros, Paul Smith, Steve Berthel, Peter Warner, Carl Nathan, Robert H. Bates
ACS Infectious Disease, 2022, 8, 557–573
254
Sub-site Ligand Recognition and Cooperativity in the TPP Riboswitch: Implications for Fragment-Linking in RNA Ligand Discovery
Meredith Zeller, Ashok Nuthanakanti, Kelin Li, Jeffrey Aubé, Alexander Serganov, and Kevin Weeks
ACS Chemical Biology, 2022, 17, 438–448
253
Single-Cell Transcriptional Profiling Reveals Signatures of Helper, Effector, and Regulatory MAIT Cells during Homeostasis and Activation
Charles Kyriakos Vorkas, Chirag Krishna, Kelin Li, Jeffrey Aubé, Daniel W. Fitzgerald, Linas Mazutis, Christina S. Leslie, and Michael S. Glickman
Journal of Immunology, 2022, 208, 1042–1056
252
In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas
Samantha Ottavi, Sarah M. Scarry, John Mosior, Yan Ling, Julia Roberts, Amrita Singh, David Zhang, Laurent Goullieux, Christine Roubert, Eric Bacque, H. Rachel Lagiakos, Jeremie Vendome, Francesca Moraca, Kelin Li, Andrew J. Perkowski, Remya Ramesh, Matthew M. Bowler, William Tracy, Victoria A. Feher, James C. Sacchettini, Ben S. Gold, Carl F. Nathan, aand Jeffrey Aubé
Journal of Medicinal Chemistry, 2022, 65, 1996–2022
251
Generation of the AD Informer Set: Chemical Tools to Facilitate Alzheimer’s Disease Drug Discovery
Frances M. Potjewyd, Joel K. Annor-Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles Travis Moerk, Felix Nwogbo, Kenneth H. Pearce Jr., Timothy Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman
Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2021, 17, e051113
250
Enzymatic Synthesis of Diverse Heterocycles by a Noncanonical Nonribosomal Peptide Synthetase
Gina Morgan, Kelin Li, Drake Crawford, Jeffrey Aubé, and Bo Li,
ACS Chemical Biology, 2021, 16, 2776–2786
Publications
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