Recent Publications

239
Targeting the Interaction Between RNA-binding Protein HuR and FOXQ12 Suppresses Breast Cancer Invasion and Metastasis
Xiaoqing Wu, Gulhumay Gardashova, Lan Lan, Shuang Han, Cuncong Zhong, Rebecca T. Marquez, Lanjing Wei, Spencer Wood, Sudeshna Roy, Ragul Gowthaman, John Karanicolas, Fei P. Gao, Dan A. Dixon, Danny R. Welch, Ling Li, Min Ji, Jeffrey Aubé and Liang Xu
Communications Biology volume 3, Article number: 193 (2020)
238
HuR reduces radiation-induced DNA damage by enhancing expression of ARID1A
Daniel Andrade, Meghna Mehta, James Griffith, Sangphil Oh, Joshua Corbin, Anish Babu, Supriyo De, Allshine Chen, Sanam Husain, Yan Zhao, Sudeshna Roy, Liang Xu, Jeffrey Aubé, Ralf Janknecht, Myriam Grospe, Terence Herman, Rajagopal Ramesh, And Anupama Munshi
Corbin, Anish Babu, Supriyo De, Allshine Chen, Sanam Husain, Yan Zhao,
Sudeshna Roy, Liang Xu, Jeffrey Aube, Ralf Janknecht, Myriam Gorospe, Terence
Herman, Rajagopal Ramesh, and Anupama Munshi
J. Org. Chem. 2019, 84, 6, 3647-3651
237
MAIT Cells are Imprinted by the Microbiota in Early Life and Promote Tissue Repair
Michael G. Constantinides, Verena M. Link, Samira Tamoutounour, Andrea C. Wong, P. Juliana Perez-Chaparro, Seong Ji Han, Y. Erin Chen, Kelin Li, Sepideh Farhat, Antonin Weckel, Siddharth R. Krishnamurthy, Ivan Vujkovic-Cvijin, Jonathan L. Linehan, Nicolas Bouladoux, E. Dean Merrill, Sobhan Roy, Daniel J. Cua, Erin J. Adams, Avinash Bhandoola, Tiffany C. Scharschmidt, Jeffrey Aubé, Michael A. Fischbach, and Yasmine Belkaid
Science, 2019, 366, eaax6624
236
Can They Imagine the Future? A Qualitative Study Exploring the Skills Employers Seek in Pharmaceutical Sciences Doctoral Graduates
Jacqueline E. McLaughlin, Lana M. Minshew, Daniel Gonzalez, Kelsey Lamb, Nicholas J. Klus, Jeffrey Aubé, Wendy Cox, Kim L. R. Brouwer
PLOS One, 2019, online
235
Tumor Suppressor TET2 Promotes Cancer Immunity and Immunotherapy Efficacy
Yan-ping Xu, Lei Lv, Ying Liu, Matthew D. Smith, Wen-Cai Li, Xian-ming Tan, Meng Cheng, Zhijun Li, Michael Bovino, Jeffrey Aubé, and Yue Xiong
Journal of Clinical Investigation, 2019, in-press review
234
Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA
Landys Lopez Quezada, Sandra Silve, Mark Kelinske, Amir Liba, Constantino Diaz Gonzalez, Martin Kotev, Laurent Goullieux, Stephanie Sans, Christine Roubert, Sophie Lagrange, Eric Bacqué, Cedric Couturier, Alain Pellet, Isabelle Blanc, Marlène Ferron, Fabrice Debu, Kelin Li, Jeffrey Aubé, Julia Roberts, David Little, Yan Ling, Jun Zhang, Ben Gold, and Carl Nathan
mBio, 2019, 10, e01405-19
233
Revisiting the β-Lactams for Tuberculosis Therapy: A Compound–compound Synthetic Lethality Approach
Shiqi Xiao, Haidan Guo, Warren Weiner, Clinton Maddox, Chunhong Mao, Hendra Gunosewoyo, Shaaretha Pelly, E. Lucile White, Lynn Rasmussen, Frank Schoenen, Jeffrey Aubé, William Bishai, and Shichun Lun
Antimicrobial Agents and Chemotherapy, 2019, online.
232
Preclinical Testing of Nalfurafine as a Potential Adjuvant to Reduce the Addictive Potential of the Mu Opioid Receptor-targeting Analgesic Morphine
Shane W. Kaski, Joshua D. Gross, Kristen R. Trexler, Kim Wix, Aubrie A. Harland, Thomas Edward Prisinzano, Jeffrey Aubé, Steven G. Kinsey, Terry Kenakin, David Siderovski, and Vincent Setola
Journal of Pharmacology and Experimental Therapeutics, 2019, online
231
Target Deconvolution of a Multikinase Inhibitor with Anti-Metastatic Properties Identifies TAOK as a Key Contributor to a Cancer Stem Cell-like Phenotype
Yansong Bia, Yaroslav Teper, Lesley A. Mathews Griner, Taylor J. Aiken,, Vivek Shukla, Rajarshi Guha, Paul Shinn, Hong-Wu Xin, Holger Pflicke, Astin Powers, Dandan Li, Jian-kang Jiang, Paresma Patel, Steven A. Rogers, Jeffrey Aubé, Marc Ferrer, Craig J. Thomas, and Udo Rudloff
Molecular Cancer Therapeutics, 2019, accepted

230
Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis
Landys Lopez Quezada, Kelin Li, Stacey L. McDonald, Quyen Nguyen, Andrew J. Perkowski, Cameron W. Pharr, Ben Gold, Julia Roberts, Kathrine McAulay, Kohta Saito, Selin Somersan Karakaya, Prisca Elis Javidnia, Esther Porras de Francisco, Manuel Marin Amieva, Sara Palomo Diaz, Alfonso Mendoza Losana, Matthew Zimmerman, Hsin-Pin Ho Liang, Jun Zhang, Veronique Dartois,Stéphanie Sans, Sophie Lagrange, Laurent Goullieux, Christine Roubert, Carl Nathan, and Jeffrey Aubé
ACS Infectious Diseases, 2019, ASAP.
229
The HuR CMLD-2 Inhibitor Exhibits Antitumor Effects via MAD2 Downregulation in Thyroid Cancer Cells
Lorenzo Allegri, Federica Baldan, Sudeshna Roy, Jeffrey Aubé, Diego Russo, Sebastiano Filetti, and Giuseppe Damante
Scientific Reports, 2019, 9, article number 7374
228
Synthesis and Antibacterial Evaluation of Cephalosporin Isosteres
Drew J. Cesta, Selin Somersan Karakaya, Kohta Saito, Prisca E. Javidnia, Julia Roberts, Yan Ling, Ben S. Gold, Landys Lopez Quezada, David Zhang, Tigran M. Abramyan, Dmitri B. Kireev, Jeffrey Aubé, and Sarah M. Scarry
Asian Journal of Organic Chemistry, 2019, 8, 1053–1057
227
Effect of C-2 Substitution on the Stability of Non-traditional Cephalosporins in Mouse Plasma
Matthew Zimmerman, Stacey L. McDonald, Hsin-Pin Ho-Liang, Patrick Porubsky, Quyen Nguyen, Cameron W. Pharr, Andrew J. Perkowski, Robert Smith, Frank J. Schoenen, Ben S. Gold, David Zhang, Carl F. Nathan, Véronique Dartois, and Jeffrey Aubé
Journal of Antibiotics, 2019, 72, 469–475
226
Synthesis of the Non-ribosomal Peptide Phevalin and Analogs
Remya Ramesh, Michael T. Bovino, Yibin Zeng, and Jeffrey Aubé, Journal of Organic Chemistry
Journal of Organic Chemistry, 2019, 84, 3647–3651
225
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition
Elaine Ballinger, John Mosior, Travis Hartman, Kristin Burns-Huang, Ben Gold, Roxanne Morris, Laurent Goullieux, Isabelle Blanc, Julien Vaubourgeix, Sophie Lagrange, Laurent Fraisse‖, Stéphanie Sans, Cedric Couturier, Eric Bacqué, Kyu Rhee, Sarah M. Scarry, Jeffrey Aubé, Guangbin Yang, Ouathek Ouerfelli, Dirk Schnappinger, Thomas R. Ioerger, Curtis A. Engelhart, Jennifer A. McConnell, Kathrine McAulay, Allison Fay, Christine Roubert, James Sacchettini, and Carl Nathan
Science, 2019, 363, 498 and eeau8959

Publications