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Recent Publications
273
Redirecting Raltitrexed from Cancer Cell Thymidylate Synthase to Mycobacterium tuberculosis Phosphopantetheinyl Transferase.
Amrita Singh, Samantha Ottavi, Inna Krieger, Kyle Planck, Andrew Perkowski, Takushi Kaneko, Andrew M. Davis, Christine Suh, David Zhang, Laurent Goullieux, Alexander Alex, Christine Roubert, Mark Gardner, Marian Preston, Dave M. Smith, Yan Ling, Julia Roberts, Bastien Cautain, Anna Upton, Christopher B. Cooper, Natalya Serbina, Zaid Tanvir, John Mosior, Ouathek Ouerfelli, Guangli Yang, Ben S. Gold, Kyu Y. Rhee, James C. Sacchettini, Nader Fotouhi, Jeffrey Aubé, and Carl Nathan
Science Advances, 2024, 10, eadj6406.
272
The Hybrid Antibiotic Thiomarinol A Overcomes Intrinsic Resistance in Escherichia Coli Using a Privileged Dithiolopyrrolone Moiety.
Rachel M. Johnson, Kelin Li, Xiaoyan Chen, Gina L. Morgan, Jeffrey Aubé, and Bo Li
ACS Chemical Biology, 2024, 10, 582–593.
271
Mixed, Non-classical Behavior in a Classic Allosteric Protein.
Paul J. Sapienza, Jeffrey P. Bonin, Dinusha H. P. Jinasena, Kelin Li, Henry Dieckhaus, Konstantin I. Popov, Jeffrey Aubé, and Andrew L. Lee
Proceedings of the National Academy of Sciences, USA, 2023, 120, e2308338120
270
Type I Interferons Drive MAIT Cell Functions Against Bacterial Pneumonia.
Juan Lopez-Rodriguez, Steven Hancock, Kelin Li, Stefania Crotta, Christopher Barrington, Alejandro Suárez-Bonnet, Simon Priestnall, Jeffrey Aubé, Andreas Wack, Paul Klenerman, Jose Bengoechea, and Patricia Barral
Journal of Experimental Medicine, 2023, 220, e20230037
269
Targeting RNA-binding Protein HuR to Inhibit the Progression of Renal Tubular Fibrosis.
Zhimin Huang, Simeng Liu, Anna Tang, Xiaoqing Wu, Jeffrey Aube, Liang Xu, and Yufeng Huang
Journal of Translational Medicine, 2023, 21, article number 428.
268
Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas.
Samantha Ottavi, Kelin Li, Jackson G. Cacioppo, Andrew J. Perkowski, Remya Ramesh, Ben S. Gold, Yan Ling, Julia Roberts, Amrita Singh, David Zhang, John Mosior, Laurent Goullieux, Christine Roubert, Eric Bacqué, James C. Sacchettini, Carl F. Nathan, and Jeffrey Aubé
ACS Medicinal Chemistry Letters, 2023, 14, 970–976.
267
Functional Inhibition of the RNA-binding Protein HuR Sensitizes Triple-negative Breast Cancer to Chemotherapy.
Lanjing Wei, Qi Zhang, Cuncong Zhong, Lily He, Yuxia Zhang, Ahlam M. Armaly, Jeffrey Aubé, Danny R. Welch, Liang Xu, and Xiaoqing Wu
Molecular Oncology, 2023, 17, 1962–1980.
266
Enhancing Mucosal-Associated Invariant T Cell Function and Expansion with Human Selective Serum.
Daniel Labuz, Jackson Cacioppo, Kelin Li, Jeffrey Aubé, and Daniel T. Leung
ImmunoHorizons, 2023, 7, 116-124
265
Small Molecules Targeting the RNA-binding Protein HuR Inhibit Tumor Growth in Xenografts
Xiaoqing Wu, Remya Ramesh, Jinan Wang, Youguang Zheng, Ahlam M. Armaly, Lanjing Wei, Minli Xing, Sudeshna Roy, Lan Lan, Fei Philip Gao, Yinglong Miao, Liang Xu, and Jeffrey Aubé
Journal of Medicinal Chemistry, 2023, 66, 2032–2053.
264
HuR-dependent Expression of Wisp1 Is Necessary for TGF-Induced Cardiac Myofibroblast Activity
Lisa C Green, Samuel Slone, Sarah R. Anthony, Adrienne Guarnieeri, Sharon Parkins, Shannon M. Shearer, Michelle L. Nieman, Sudeshna Roy, Jeffrey Aubé, Xiaoqing Wu, Liang Xu, Onur Kanisicak, and Michael Trantner
Journal of Molecular and Cellular Cardiology, 2023, 174, 38–46
263
HFIP in Organic Synthesis
Hashim F. Motiwala, Ahlam M. Armaly, Jackson G. Cacioppo, Thomas C. Coombs, Kimberly Koehn, Verrill M. Norwood IV, and Jeffrey Aubé
Chemical Reviews, 2022, 122, 12544–12747
261
Use of a MAIT-Activating Ligand, 5-OP-RU, as a Mucosal Adjuvant in a Murine Model of Vibrio cholerae O1 Vaccination
Owen Jensen, Shubhanshi Trivedi, Kelin Li, Jeffrey Aubé, J. Scott Hale, Edward T. Ryan, and Daniel T. Leung
Pathogens and Immunology, 2022, 7, 122–144
260
Small Molecule Disruptors of Mutant Huntingtin–Calmodulin Protein–Protein Interaction Attenuate Deleterious Effects of Mutant Huntingtin
Khushboo Kapadia, Ashley E. Trojniak, Kenneth B. Guzmán Rodríguez, Nicholas J. Klus, Coral Huntley, Peter McDonald, Anuradha Roy, Kevin J. Frankowski, Jeffrey Aubé, and Nancy A. Muma
ACS Chemical Neuroscience, 2022, 13, 2315–2337
259
Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis
Kevin J. Frankowski, Samarjit Patnai, Chen Wang, Noel Southall, Dipannita Dutta, Soumitta De, Dandan Li, Christopher Dextras, Yi-Han Lin, Marthe Bryant-Connah Danielle Davis, Feijun Wang, Leah M. Wachsmuth, Pranav Shah, Jordan Williams, Md Kabir, Edward Zhu, Bolormaa Baljinnyam, Amy Wang, Xin Xu, John Norton, Marc Ferrer, Steve Titus, Anton Simeonov, Wei Zheng, Lesley A. Mathews Griner, Ajit Jadhav, Jeffrey Aubé, Mark J. Henderson, Udo Rudloff, Frank J. Schoenen, Sui Huang, Juan J. Marugan
Journal of Medicinal Chemistry, 2022, 65, 8303–8331
Publications
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